Clinical Impact of Overexpression of FOXP3 and WT1 on Disease Outcome in Egyptian Acute Myeloid Leukemia Patients

Asian Pac J Cancer Prev · 2016 · PMC5454620 · PMID 27893200

Europe PMC DOI

hedged sentences

0.0020

closest p · 0.0× alpha

0.0550

boldest claim

The sentences

highly significantp = 0.002actually significant

In M2+M4+M5 FAB-subtype, FOXP3 expression was mostly down-regulated (74.2%) while M0+M1 (68.2%) FOXP3 was overexpressed the different was statistically highly significant (p = 0.002), when using Pearson chi-square method.

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borderline significancep=0.055so close (0.05 < p ≤ 0.1)

Splenomegaly was the only factor with borderline significance (p=0.055) HR 3.4 (95%CI 0.97 – 11.9) which affects the DFS and TLC was the only independent factor that significantly affects the OS in the adult AML group (p =0.024) HR 2.2(95%CI 1.1 – 4.5).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.