highly significantP -value <10 −12
The overrepresentation of mutations in subtelomeric regions is highly significant in O. tauri (10 vs. 94 mutations in subtelomeric versus nonsubtelomeric regions, Fisher exact test, P -value <10 −12 ), B. prasinos (8 vs. 24 mutations, Fisher exact test, P -value <10 −12 ) and M. pusilla (4 vs. 81 mutations, Fisher exact test, P -value <10 −4 ).