Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women With Mechanical Heart Valves.

J Am Coll Cardiol · 2017 · PMC5457289 · PMID 28571631

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Compared with women who received a VKA regimen, the average risk of an adverse maternal event was significantly higher among women who received an LMWH regimen (RAR: 3.1; 95% CI: 1.3 to 7.5) or a regimen of UFH and VKA (RAR: 3.1; 95% CI: 1.5 to 7.4), with a trend toward significance in women who received a regimen of LMWH and VKA (RAR: 3.2; 95% CI: 0.9 to 8.8) ( Figure 4 ).

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