Splenic marginal zone lymphoma: a literature review of diagnostic and therapeutic challenges.

Rev Bras Hematol Hemoter · 2017 · PMC5457460 · PMID 28577652

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an increasing trendno p-value reported

8 Gender prevalence is controversial, 6 , 7 but there is an increasing trend to male predominance. 8 , 10 , 11 The association of SMZL with hepatitis C (HCV) is common in the south of Europe, 3 , 12 , 13 and lymphoma development is usually triggered by the glycoprotein E2 of the virus that stimulates CD81 in B cells. 5 , 6 , 13 Although there are controversial data in Brazi

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