Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling.

Oncotarget · 2017 · PMC5458186 · PMID 28415686

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highly significantno p-value reported

Therefore, to find out the agents that can selectively inhibit activation of NLRP3 inflammasome will be highly significant for prevention and treatment of inflammation-related diseases.

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