Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.

Oncotarget · 2017 · PMC5458272 · PMID 28389630

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highly significantno p-value reported

Under these conditions, we measured a highly significant reduction in the p-Thr288-Aurora-A signal in cultures treated with both C20 and C23 compounds compared to controls (Figure 6B ), confirming that both compounds impaired Aurora-A activation.

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