The effects of stimulus novelty and negativity on BOLD activity in the amygdala, hippocampus, and bed nucleus of the stria terminalis.

For pairwise comparisons between Trial types within Novelty, there was a significantly higher response to repeated images on the fifth vs the first repetition (excluding the initial presentation), X 2 (1) = 11.34, P = 0.015, as well as a possible trend toward a greater response to repeated image on the third vs the first repetition, X 2 (1) = 7.86, P = 0.1 (Holm–Bonferroni corrected).

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Contrary to these predictions, the only significant effect of anxiety involved a marginal trend toward anxiety predicting less activity in the BNST than in the hippocampus.

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