highly significantP =1.64×10 -54
We also performed eQTL analysis using published data (Blood eQTL Browser: http://genenetwork.nl/bloodeqtlbrowser/ ), and found that three candidate variants showed highly significant association with the expression of EP300 in blood ( P =1.64×10 -54 for rs2076578, P =3.63×10 -54 for rs575825, and P =3.26×10 -54 for rs2143694), suggesting that these variants are probably involved in the expression regulation of EP300 .