Variable frequency of <i>LRRK2</i> variants in the Latin American research consortium on the genetics of Parkinson's disease (LARGE-PD), a case of ancestry.

3 , 12 , 17 , 18 In a small pilot study we also observed that the LRRK2- p.Q1111H SNP, which is common in some Latin American populations, occurred at an increased frequency in PD patients, though the difference was not quite significant. 19 Thus, whether this variant represents a PD risk factor in Latino populations remains unclear.

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