Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance <i>Mycobacterium tuberculosis</i> peptides in human serum.

Clin Proteomics · 2017 · PMC5460347 · PMID 28592925

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highly significantno p-value reported

Overall, the optimized MRM method including the addition of labeled standards and iRTS and the optimized data analysis algorithm, allowed us to reduce our original candidate biomarker list from 41 to 20 highly significant peptides in the context of active TB disease.

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