Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes.

Kidney renal papillary cell carcinoma (KIRP), uterine corpus endometrial cancers (UCECs), rectal adenocarcinoma (READ), cervical squamous cell cancers, breast cancers (BRCA) and liver hepatocellular carcinomas also all show a trend toward increased expression in mutant samples with KIRP displaying near significance (Figure S2A and B).

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The differences were significant in both the lung and pancreas samples, but not in the colon samples, although the KRAS4A is borderline significant in that tissue (.055).

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