Efficacy and Safety of Mycobacterium indicus pranii as an adjunct therapy in Category II pulmonary tuberculosis in a randomized trial.

Results of lymphocyte proliferation were also reflected in the IFN-γ secretion which increased consistently from Day 0 and almost doubled in 3 months and remained high till 12 month in the MIP group while on the contrary, the amount of secreted IFN-γ showed a decreasing trend in the placebo group from Day 0 onward till 6 month (Supplementary Figure 3 ).

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tb antigen showed an increasing trend in the MIP group from Day 0 to 6 month in follow-up samples on M . tb stimulation while no change was seen in the placebo group, however, the difference was not statistically significant (Supplementary Figure 2 ).

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