Lamination of microfibrous PLGA fabric by electrospinning a layer of collagen-hydroxyapatite composite nanofibers for bone tissue engineering.

4 ) has made it clear that on increasing the applied voltage from 12 kV to 18 kV between needle and the grounded collector, the fiber diameter has shown a decreasing trend from 5.2 μm to 3.4 μm.

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7 a, b, c ) have indicated that on increasing the amount of nHA in collagen, the nHA nanorods have started the formation of aggregates instead of showing uniform distribution of nHA in the scaffolds. The extent of formation of aggregates of nHA has shown an increasing trend in their size on increasing the amount of nHA from 3.8 to 5.0 wt%, which is apparent on comparing the scaffolds electrospun using collagen solution containing 4.4 wt% and 5.0 wt% of nHA (Fig. 7b, c ).

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