5-Aza-2'-deoxycytidine in the medial prefrontal cortex regulates alcohol-related behavior and Ntf3-TrkC expression in rats.

PLoS One · 2017 · PMC5470731 · PMID 28614398

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a decreasing trendno p-value reported

At 28 d and 35 d, a decreasing trend (WE:5824.94±144.86cm VS AE:4494.54±180.74 cm at 28d; WE:5602.01±222.11cm VS AE:3635.22±208.12cm at 35d) in the total distance was detected in alcohol-exposure rats, which reflected the inhibitory effects of chronic alcohol exposure.

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an increasing trendno p-value reported

Compared with the water-exposure groups, there was an increasing trend (WE:5457.75±192.75 cm VS AE:7017.95±213.73 cm) in the total distance travelled of alcohol-exposure rats at 7 d, which indicated that short-term alcohol exposure could induce locomotor stimulatory effects.

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