Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer.

Oncotarget · 2017 · PMC5471010 · PMID 28410235

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not quite significantno p-value reported

Upon further examination of the different immune cell subgroups, the Cysltr1 −/− colons displayed a significant decreased CD4 and Arg-1 mRNA expression, which is indicative of mainly CD4 + T cells and type-2 macrophages, respectively, with a modest decrease in CD8 mRNA levels that was not quite significant (Figure 5 ).

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