Barely Significant
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Low-dose methotrexate in sickle-cell disease: a pilot study with rationale borrowed from rheumatoid arthritis.

Exp Hematol Oncol · 2017 · PMC5474854 · PMID 28638723

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highly significantno p-value reported
The median CRP levels ranged from 0.84 mg/dL (week 0) to 0.55 mg/dL (week 12) ( P = 0.359, Table 3 ). Among the inflammatory markers tested, MTX treatment had a highly significant impact on two chemokines, that possess both chemotactic and angio-modulatory properties.

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