Serum Glutamate Is a Predictor for the Diagnosis of Multiple Sclerosis.

In the healthy controls, the normal level was predominant ( n = 16, 64%) over the hyperlevel ( n = 9, 36%), with a highly significant difference ( p = 0.001, p < 0.01).

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More recently, however, research has begun to indicate that changes in glutamate levels and glutamate receptor expression may be significant earlier in the disease process than originally thought [ 10 ].

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