Is Ep-CAM Expression a Diagnostic and Prognostic Biomarker for Colorectal Cancer? A Systematic Meta-Analysis.

EBioMedicine · 2017 · PMC5478257 · PMID 28558958

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a positive trendno p-value reported

The loss of Ep-CAM expression was significantly associated with tumor differentiation ( Kim et al., 2016 , Kim et al., 2014 , Gosens et al., 2007 , Went et al., 2006 ), and another study demonstrated a positive trend towards an association between the loss of Ep-CAM expression and tumor differentiation ( Lugli et al., 2010 ).

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