IGF-II analog, a weak agonist, reduced the crypt cell abundance while NBI 31772 (an agent that displaces IGFs from IGFBPs) increased it significantly and R 3 -IGF-I doubled the number of crypt cells per 10X field (also highly significant) while none of the treatments significantly altered the abundance of C2 negative cells.
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A methodology for distinguishing divergent cell fates within a common progenitor population: adenoma- and neuroendocrine-like cells are confounders of rat ileal epithelial cell (IEC-18) culture.
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