A novel pathway-based distance score enhances assessment of disease heterogeneity in gene expression.

BMC Bioinformatics · 2017 · PMC5480187 · PMID 28637421

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a decreasing trendno p-value reported

When δ = 1.5, the success rate of the pathway-based distance score has a decreasing trend, indicating that high correlation between genes makes it harder to identify the correct number of clusters when there is a big difference between the true classes.

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