High-resolution profiles of gene expression and DNA methylation highlight mitochondrial modifications during early embryonic development.

J Reprod Dev · 2017 · PMC5481627 · PMID 28367907

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an increasing trendno p-value reported

Focusing on the MeDIP-qPCR results from both hyper- ( ND5 , ND6 ) and hypomethylated ( 12S rRNA ) regions, as well as a control region (D-loop), we observed that each of these regions was significantly methylated, with an increasing trend during the transition from E7.5 to E10.5 ( Fig. 6D ).

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