Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency promotes IL-17- and TLR4-dependent arthritis.

Compared with WT microbiota, we found a highly significant overrepresentation of the genus Helicobacter ( P = 0.004, Bonferroni corrected), and a significant underrepresentation of the genus Prevotella ( P = 0.008, Bonferroni corrected) (Fig. 2 and Additional file 1 : Table S2).

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