Characterization of constitutive and acid-induced outwardly rectifying chloride currents in immortalized mouse distal tubular cells.

Conversely, when [Cl − ] i was reduced from 140 mM to 10 mM by replacement with methanesulfonate (CH 3 SO 3 − ), a highly significant −40.6 ± 4.5 mV shift in the reversal potential was observed (iI to iXI) ( Fig. 1 E, F).

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