A simple mathematical approach to the analysis of polypharmacology and polyspecificity data.

F1000Res · 2017 · PMC5482344 · PMID 28690829

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may be significantno p-value reported

More importantly, in many cases the number of possible drug-target pairs whose activity status is unknown may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.