Barely Significant
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Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts.

Nucleic Acids Res · 2005 · PMC548366 · PMID 15687385

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probable significanceno p-value reported
Probable significance of the strictly ordered binding of Cdc6 and Cdt1 to chromatin Re-licensing must be avoided in the normal cell cycle, and there seems to be a number of mechanisms to ensure this.

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