Both troponin T and CpK-Mb reached highly significant values in the control group compared with the trimetazidine group at the 4 time points analyzed: 5 min after aortic declamping, and at subsequent 12, 24, and 48 h. 46 In an RCT, patients ( n = 40) undergoing elective CABG were treated with trimetazidine or placebo.
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Modulation of myocardial energetics: An important category of agents in the multimodal treatment of coronary artery disease and heart failure.
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