Proteomic High Affinity Zn<sup>2+</sup> Trafficking: Where Does Metallothionein Fit in?

Int J Mol Sci · 2017 · PMC5486110 · PMID 28629147

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may not be significantno p-value reported

Thus, it was proposed that Cd 2+ reacts with Zn n -MT, causing the displacement of Zn 2+ and making it available for reaction with MTF-1 [ 112 ]: (22) n Cd 2+ + Zn n -MT ⥂ Cd n -MT + n Zn 2+ Missing from this hypothesis was the recognition that the concentration of Zn n -MT may not be significant in some cells; yet induction of MT biosynthesis occurs upon their exposure to Cd 2+ .

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