Histone posttranslational modifications predict specific alternative exon subtypes in mammalian brain.

PLoS Comput Biol · 2017 · PMC5487056 · PMID 28609483

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highly significantno p-value reported

Using this method we have applied a single statistical test to the association of ChIP-Seq and RNA-Seq data within a brain-derived dataset to find that there are highly significant associations between alternative splicing and the specific histone marks H3K36me3 and H3K4me1.

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