Synchronized HIV assembly by tunable PIP<sub>2</sub> changes reveals PIP<sub>2</sub> requirement for stable Gag anchoring.

Elife · 2017 · PMC5495570 · PMID 28574338

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Quantification of Gag clusters at the ventral PM of DMSO (n = 27) or rCD1 treated (n = 26) cells revealed a pronounced (80%) and highly significant (p<0.0001) reduction of Gag clusters in PM PI(4,5)P 2 depleted cells compared to control cells ( Figure 1F ).

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