It includes 13 highly significant independent predictors of mortality: age, ejection fraction, NYHA class, serum creatinine, diabetes, beta-blocker usage, systolic blood pressure, body mass, time since diagnosis, current smoking status, presence of chronic obstructive pulmonary disease, gender, and usage of ACE-inhibitors or angiotensin-receptor blockers [ 55 ].
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Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials.
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