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Cathepsin B inhibitor improves developmental competency and cryo-tolerance of in vitro ovine embryos.

BMC Dev Biol · 2017 · PMC5496377 · PMID 28676034

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a decreasing trendno p-value reported
Furthermore, expression of Cathepsin B show a decreasing trend from oocyte toward blastocyst stage.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.