When we undertook GO analysis in group A genes, “intracellular” ( P = 0.0092), “intracellular part” ( P = 0.0021), “cytoplasm” ( P = 0.0021) and “cytoplasmic part” ( P = 0.046) were identified as significantly enriched GO terms in comedo DCIS compared to all the DCIS cases, and “protein binding” ( P = 0.075) was marginally significant (Fig. 1 b).
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Cytochrome c1 in ductal carcinoma in situ of breast associated with proliferation and comedo necrosis.
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