Are Polymorphisms in Genes Relevant to Drug Disposition Predictors of Susceptibility to Drug-Induced Liver Injury?

Pharm Res · 2017 · PMC5498650 · PMID 28028769

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borderline significantno p-value reported

Studies on the relationship between CYP genotype and development of DILI following overdose are very limited but one relatively large study reported a borderline significant relationship between CYP3A5*1 in patients who took an intentional overdose and developed acute liver failure ( 8 ).

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