Barely Significant
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Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.

Oncogene · 2017 · PMC5501768 · PMID 28263969

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highly significantno p-value reported
The increased levels of P-FRA1, P-ERK, P-RSK and decrease in cleaved poly ADP ribose polymerase was highly significant as shown by densitometry measurements taken from three independent experimental replicates ( Supplementary Figure 3 ).

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