In a longitudinal study comprising 2422 normoglycemic individuals followed for 12 years, plasma levels of 3 branched-chain amino acids (BCAA; isoleucine, leucine, valine) and 2 aromatic amino acids (tyrosine and phenylalanine) exhibited highly significant associations with the future development of diabetes [ 4 ].
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Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals.
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