PSCA, Cox-2, and Ki-67 are independent, predictive markers of biochemical recurrence in clinically localized prostate cancer: a retrospective study.

In addition, bcl-2 expression might be further evaluated in a study with a longer follow-up period and more patients as this marker almost reached statistical significance as a predictive marker of BCR in multivariate analysis ( P = 0.051; Table 2 ) and there was a significant difference in BCR-free survival between patients with positive and negative bcl-2 tumor expression ( P = 0.0183, data not shown).

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