Polydextrose changes the gut microbiome and attenuates fasting triglyceride and cholesterol levels in Western diet fed mice.

Sci Rep · 2017 · PMC5509720 · PMID 28706193

Europe PMC DOI

hedged sentences

0.0523

closest p · 1.0× alpha

0.0611

boldest claim

The sentences

nearly significantp = 0.0523so close (0.05 < p ≤ 0.1)

Npc11 , Npc1, Acsl3 , Fabp2 and Ppara were also differentially regulated expression in the different parts of the small intestine: Npcl1 and Npc1 upregulated in jejunum, Acsl3 upregulated in ileum and Fabp2 downregulated in jejunum, Furthermore, PPARα expression was nearly significantly reduced by PDX in jejunum (p = 0.0523) and significantly in ileum (p = 0.0434).

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not quite significantp = 0.0611so close (0.05 < p ≤ 0.1)

Polydextrose treatment in Western diet also increased the relative abundance of Verrucomicrobia (2.6% in WD + PDX versus 0.42% in WD), but this was not quite significant (p = 0.0611).

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