Anti-citrullinated protein antibody positive rheumatoid arthritis is primarily determined by rheumatoid factor titre and the shared epitope rather than smoking per se.

PLoS One · 2017 · PMC5510819 · PMID 28708862

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not achieve significancep = 0.06so close (0.05 < p ≤ 0.1)

However, in RF negative patients, the rate of ACPA positivity appeared to have a greater dependence on number of SE copies, although it did not achieve significance (57% vs 73%, p = 0.06).

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