Barely Significant
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Experimental evidence reveals the UCP1 genotype changes the oxygen consumption attributed to non-shivering thermogenesis in humans.

Sci Rep · 2017 · PMC5514118 · PMID 28717127

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highly significantno p-value reported
Nonetheless, this study must be highly significant from the perspective of having shown experimentally the association between the genotype (haplotype) of UCP1 and the change in oxygen consumption caused by NST using healthy subjects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.