Decline of heterozygosity in a large but isolated population: a 45-year examination of moose genetic diversity on Isle Royale.

However, observed heterozygosity displayed a marginally significant, negative relationship over time: observed heterozygosity was 0.53 in 1960–65 and 0.47 in 2000–05 ( Table 1 , Table 2 , Fig. 3 ).

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