In univariate and multivariate Cox proportional hazards analysis, both immune cell infiltration and m PDCD1 methylation as continuous variables further served as highly significant prognostic factors in HNSCC, thereof m PDCD1 and CD4 pos T lymphocytic infiltrates being independent and as powerful as pT and pN categories.
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PDCD1 (PD-1) promoter methylation predicts outcome in head and neck squamous cell carcinoma patients.
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