borderline significancep = 0.052
Interestingly, although the presence of HPR had no influence on plasma level of MMP-2 as well as its release from activated platelets (as indicated above), diabetic subjects with HPR (meeting MEA criteria) showed an increased plasma MMP-2 in comparison to diabetics without HPR (213.6 ± 76.1 versus 164.8 ± 54.6, borderline significance p = 0.052). 4.