1 In 2010, Bolland et al 2 reported a meta‐analysis of 8 randomized clinical trials in which calcium supplements in monotherapy (CaM) were associated with a significant increased risk of acute myocardial infarction (AMI; relative risk: 1.27; 95% confidence interval [CI], 1.01–1.59) and a marginally nonsignificant increased risk of stroke (relative risk: 1.12; 95% CI, 0.92–1.36).
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Risk of Ischemic Stroke Associated With Calcium Supplements With or Without Vitamin D: A Nested Case-Control Study.
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