The other three peptides, LRS8, VIP8, and YSP9 showed a similar trend as AMQ8 and EVK10 but with slightly lower responses of CD8+ IFN-γ+ T cells at 1.73×10 5 (2.4%), 1.61×10 5 (2.1%), and 1.67×10 5 cells (2.3%), respectively, but failed to reach significance ( Fig. 7C–E ).
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A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles.
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