Serum kynurenic acid is reduced in affective psychosis.

For instance, a highly significant association between the plasma and CSF concentrations of QA in IFNα-treated hepatitis C patients was reported by Raison, Miller and colleagues ( r =0.72, P <0.001). 33 Further, Brundin, Erhardt and colleagues have reported persistent reductions in KynA and increases in QA in the CSF of suicide atte

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Follow-up t-tests indicated that the healthy controls had significantly lower concentrations of CRP or a statistical trend towards lower concentrations of CRP than the MDD, BD and SzA groups.

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