Markers of disease and steroid responsiveness in paediatric idiopathic nephrotic syndrome: Whole-transcriptome sequencing of peripheral blood mononuclear cells.

J Int Med Res · 2017 · PMC5536413 · PMID 28639503

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highly significantno p-value reported

PI3Kγ, CTLA4 inhibitory signalling, the early response to TGFβ1, IL4 receptor signalling in B lymphocytes, pantothenate and CoA biosyntheses, the syndecan 3 pathway, and the mTOR signalling pathway. More stringent criteria ( P < 0.01 and >2-fold changes of expression) were applied to identify the highly significant genes in idiopathic NS.

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