extremely significantP < 0.01
As shown in Figure 2 , when AE concentration was in the 250–2000 mg/L range, AE promoted SC proliferation after treating for 24 h, 48 h, and 72 h; at a concentration of 500–2000 mg/L, cell proliferation in different groups was significantly increased by comparison with control group ( P < 0.05); when the concentrations were 1000 and 2000 mg/L, drug-treated groups showed the extremely significant difference compared to control group ( P < 0.01). 3.3.