Optimization of Submerged Fermentation Medium for Matrine Production by <i>Aspergillus terreus</i>, an Endophytic Fungus Harboring Seeds of <i>Sophora flavescens</i>, Using Response Surface Methodology.

Table 4 showed the ANOVA for response surface quadratic model and the statistical significance of the regression model, which indicated that the model was highly significant for the matrine production, as was evident from F -value (model = 19.43) with a very low probability value ( p > F ) [ 36 ].

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