Antiproliferative effect of somatostatin analogs in advanced gastro-entero-pancreatic neuroendocrine tumors: a systematic review and meta-analysis.

Oncotarget · 2017 · PMC5542298 · PMID 28402955

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

a trend towards significanceP = 0.09so close (0.05 < p ≤ 0.1)

A trend towards significance was observed in the meta-analysis in terms of treatment discontinuation ( P = 0.09; Figure 3c ), while a statistically significant difference (RR 3.79, 95% CI: 1.28 to 11.17, P = 0.02; Figure 3d ) was observed for the occurrence of biliary stones: 10.5% in the SSA vs . 2.7% in the placebo arm, respectively, with no heterogeneity recorded ( I 2 = 0, P = 0.74).

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