Production of an anti-Aβ antibody fragment in Pichia pastoris and in vitro and in vivo validation of its therapeutic effect.

PLoS One · 2017 · PMC5542431 · PMID 28771492

Europe PMC DOI

hedged sentence

0.0508

closest p · 1.0× alpha

0.0508

boldest claim

The sentences

marginal significancep = 0.0508so close (0.05 < p ≤ 0.1)

pastoris , are capable of blocking Aβ-induced toxicity in a concentration-dependent manner (two-way ANOVA p = 0.0016) with a marginal significance due to differences among mutants (two-way ANOVA p = 0.0508).

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